Takeda Returns Exclusive Rights for Gastrointestinal Assets to BioSurfaces
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Takeda Returns Exclusive Rights for Gastrointestinal Assets to BioSurfaces

Ashland, MA; September 16, 2024 – Takeda Pharmaceutical Company Limited has returned to BioSurfaces the exclusive rights in BioSurfaces’ Bio-Spun™ devices for use in gastrointestinal diseases following completion of their collaboration agreement.  The reversion includes an exclusive license from Takeda to certain technology that was jointly-developed under the terminated collaboration agreement.  The technology relates to the use of BioSurfaces’ Bio-Spun™ materials in devices for the treatment of complications related to gastrointestinal diseases.  The technology uses BioSurfaces’ Bio-Spun™ materials in three devices that BioSurfaces developed for Takeda under a research and development agreement that began in June 2017 and was terminated in May 2023.


The devices are a perianal fistula plug to heal fistula tracts as well as deliver biotherapeutics, a cell therapy delivery chamber that encapsulates target cells to deliver GI-specific biotherapeutics, and a gastric stent sheath wrap to deliver drugs for treatment of GI disease.  All three devices have completed successful preclinical assessments. 

With its reversion and license relating to these devices from Takeda now in place, BioSurfaces is seeking strategic partners to continue advancing these technologies to benefit patients suffering from complications related to gastrointestinal diseases.


“BioSurfaces has been developing and refining our technology for over 21 years.  Devices comprised of our Bio-Spun™ materials, such as the perianal fistula plug, cell therapy delivery chamber, and gastric stent sheath wrap have been shown to fully integrate with the body’s own tissue in preclinical studies, which is a major differentiator from current woven and knitted textile materials,” said Matthew Phaneuf, President and CEO of BioSurfaces. “We are excited about now having exclusive rights to these devices for gastrointestinal applications.  This reversion provides BioSurfaces the opportunity to partner with leading companies in the gastrointestinal or adjacent spaces.”  


About BioSurfaces (www.biosurfaces.us)


BioSurfaces, based in Ashland, Massachusetts, is focused on improving lives throughout the world by applying our unique Bio-Spun™ nanofiber materials paired with our decades of expertise to develop and provide a range of products that are superior to those available today.  Bio-Spun™ technology creates solutions by engineering biology with synthetic cellular matrices.  We continue to drive innovation in applications related to life science benchtop tools, stand-alone or combination medical devices and consumer products.  We also collaborate with some of the world's leading life science organizations also working in these areas. 


For more information on BioSurfaces:

Cameron Phaneuf

Director, Marketing and Sales

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